‘Yes, that is certainly about right. I seek out a Actual physical knowledge of Organic units inside a base-up way. I think you could potentially distinguish three traces of research in my group at the moment. The 1st issues chromosome framework: How will you receive a metre-very long DNA polymer folded and organised in such a microscopic mobile? Now we have made visualisation techniques that enable us to review how, for example, SMC proteins loop DNA (video on Youtube) in an effort to Establish up chromosomes.

But how do morality, the dignity of your individual, my expertise of the this means of lifetime, stick to in the motion of atoms? A purely naturalistic viewpoint fails here; a Christian perspective, I feel, is a much more acceptable strategy to interpret these elements of truth.’

, Groningen researchers current the final results in their initiatives to help make labs more sustainable and provide strategies for other labs. 

2007, first actual-time detection of strand Trade in homologous recombination by RecA; discovery of a reduced persistence length of finishes of microtubules; and fixed the system of biosensing with carbon nanotubes

2015, discovery that condensin is actually a really flexible protein framework; and first detection of DNA knots making use of nanopores

Example (three) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the movement on the DNA rod is displayed.

We form germs into kinds that deviate from their organic phenotype. Particularly, I'll clearly show our capacity to form Reside E. coli bacteria into novel styles for example rectangles, squares, triangles and circles.

2000, discovery that nanotubes can carry incredible big recent densities; fixed the controversial problem of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes

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But carbon nanotubes have remained a analysis ceesdekker.net subject of sizeable curiosity to lots of. Certainly, the outlook on working with carbon nanotubes to construct realistic gadgets, in parts like radio-frequency electronics, electronic electronics and versatile electronics, remains vivid.

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial mobile division

‘That fears the artificial cell, as Element of the Dutch BaSyC initiative. Craig Venter looked leading-down in All those times and recognized about 5 hundred genes that happen to be minimally essential for just a performing mobile. We wish to glance base-up: how can we move from the couple molecules to an entire Organic technique?

Visualization of unstained DNA nanostructures with advanced in-concentrate transmission electron microscopy approaches

2004, discovery of new physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization from the mechanical Attributes of double-stranded RNA; and 1st one-molecule examine of DNA translocation by a restriction-modification enzyme.